PureBMC® SupraPhysiologic is autologous bone marrow concentrate (BMC) that’s clinically accepted modern progenitor stem cell medicine that’s used in the treatment of various pathologies. It supports tissue healing and regeneration through a cell milieu that comprises of a concentrated combination of differentiating stem cells consisting of hematopoietic, mesenchymal, and total nucleated cells, in addition to platelets and other cell mediators and cytokines. The use of PureBMC® is a point of care minimally invasive biologic that adds the power of self-renewal and differentiation to biologic therapies for musculoskeletal pathologies, spinal disorders, chronic wound care, and critical limb ischemia and a host of other wounds and injuries. It is an effective treatment in the rapidly growing field of regenerative medicine. PureBMC® SupraPhysiologic is the state of the art in bone marrow concentrating system that leads with biologic power, safety, efficiency and clinical outcomes.